fedratinib will enhance the stage or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Adjust dose of medicines which have been CYP3A4 substrates as essential.
modafinil will reduce the extent or effect of capivasertib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Potent or average CYP3A inducers lower capivasertib exposure, which may decrease efficacy.
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Estrogen Derivatives: In patients applying merged oral contraceptive products (OCP), the maker recommends that people use an alternate way of contraception, in place of or in addition to OCP, for the duration of and until eventually one particular month just after completing modafinil therapy.
Modafinil is accustomed to assistance people who have narcolepsy, obstructive rest apnea/hypopnea syndrome (OSAHS), or change do the job sleep condition (SWSD) to stay awake throughout the day. Modafinil won't overcome these circumstances and can only perform providing you continue to choose it.
Utilizing Liquor or tobacco with particular medicines could also lead to interactions to manifest. Go over using your healthcare Skilled the usage of your medication with foodstuff, alcohol, or tobacco.
[18] Critical renal and/or hepatic impairment is understood to lead to significantly greater continuous-condition drug concentrations. Dose reduction is usually recommended in individuals with intense hepatic impairment.
PROVIGIL is contraindicated in people with known hypersensitivity to modafinil or armodafinil or its inactive substances [see WARNINGS AND Safety measures].
The advantages of microdosing Modafinil commonly are much less small Unwanted effects, a lot easier time falling asleep, and the chance to loosen up after the work is completed.
modafinil will boost the amount or result of diazepam intranasal by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Solid or moderate CYP2C19 inhibitors may well decrease fee of diazepam elimination, thus rising adverse reactions to diazepam.
Check Closely (1)voriconazole will raise the amount or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
modafinil will decrease the extent or influence of copyright topical by impacting hepatic enzyme modafinil dosage CYP2B6 metabolism. Small/Importance Not known.
The advisable dosage of modafinil tablets for people with narcolepsy or OSA is two hundred mg taken orally once per day as an individual dose each morning.
cenobamate will improve the stage or influence of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Closely. Take into consideration a dose reduction of CYP2C19 substrates, as clinically correct, when employed concomitantly with cenobamate.